Functional infringements. A chronic intoxication

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The Delay of some chemical substances in a fabric of kidneys creates conditions for their chronic influence.

At long (3-5 years) contact with hlororganiche-skimi connections develop functional infringements, can appear proteinurija, eritrotsiturija.

The Chronic intoxication is shown by lead about-teinuriej, eritrotsituriej, decrease klubochkovoj filtrations, kanaltsevoj reabsorbtsii and secretions. At 7Р· patients with allergic diseases himicheskogoproishozhdenija change of functions of kidneys (N.S.Orlov, 1974) is found out. At z patients with a chronic intoxication-troproizvodnymi toluene come to light proteinurija, erirotsiturija, tsilindrurija, and at 112 - infringement of functions of kidneys.

spectrum Change uroproteinov at the persons who were exposed to a long-term intoxication by cadmium, regarded as a sign of defeat of kidneys, describe A. Bernard with co-authors observed proteinuriju at the persons who were in contact to cadmium, which ischezalaposle the contact terminations. On occasion, on the contrary, nefropatija it is shown after the contact termination. According to W. Str and I. Noop (1977), activity increase fosfatazy in urine is a sign nefrotoksichnosti chemical substances.

From industrial physical factors, besides radiant energy, negative influence on activity of kidneys is rendered by vibration, ultrasound, high and low temperatures, currents of high frequency, a microwave, raised and lowered barometricheskoedavlenie, and also factors of space conditions. At vibrating illness at 16,2% of patients it is defined proteinurija, and at 23 - infringement of functions of kidneys. Changes of functions of kidneys under the influence of ultrasound, low and high surrounding temperature are found out.