Giperpankreatizm. The Nefrotichesky syndrome

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The Question on diagnostic value nefrobiopsii is disputable because as it is specified above, morphological changes in kidneys differ considerable variety and to establish patognomonichnye signs it is possible no means always. The chronic nephritic insufficiency caused mielomnoj nefropatiej, usually is not accompanied by a hypertensia and hypocalcium-miej that can be one of differentsialno-diagnostic signs.

At carrying out differentsialnojdiagnostiki mielomnoj nefropatii and other diseases of kidneys it is necessary to remember possibility of development of a syndrome of sharp nephritic insufficiency at such patients in connection with application rentgenokontrastnyh substances whereas spontaneously it arises at them very seldom.

It is necessary to differentiate mielomnuju nefropatiju and initially-chronic glomerulonefrit, especially proceeding with nefroticheskim a syndrome More often. The Nefrotichesky syndrome at mielomnoj nefropatii is characterised high stepenjuproteinurii (till 40-60 gsut), normo or gipoproteinemiej, gipergammaglobulinemiej; at glo-merulonefrite always there is gipoproteinemija and usually a hyperalpha-2-globulinemija. Expressed eritrotsiturii at mielomnoj nefropatii usually it is not observed.