Tumours from argentafinnyh cages. A primary tumour

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Argentafinnye of a cage produce such polipeptidnye hormones, as gastrin, sekretin, gljukagon, CERTIFICATE G, etc.

Tumours from argentafinnyh cages grow in podslizistom a layer, the small sizes and only sometimes sprout a subserous layer of guts, in the latter case is possible metastazirovanie (M.A.Sapozhnikova, 1973).

For the majority kartsinoidov are characteristic slow growth and rather later metastazirovanie in regionarnye lymph nodes and a liver, is much more rare in lungs ikosti.

The Primary tumour, and more often its metastasises in a liver produce in blood a considerable quantity serotoninaili its predecessor - 5-oksitriptofana, and also other biologically active substances. Serotonin in turn promotes an exit gistamina from corpulent cages gistamin, kininy, circulating in blood, cause difficult simptomokompleks kartsinoidnogo a syndrome (n.Menshikov with soavt., 1972). j this syndrome a certain role igrjart naja insufficiency of nicotinic acid, kotorajaobrazuetsja from тpиптфaJaJJIPxклькпpисадциноиде tripto-fdtguaThodutsjana synthesis serotonina.

In most cases kartsinoid long time clinically is not shown. At tumour localisation in guts or an appendix its growth can cause the phenomena of intestinal impassability or an appendicitis. The basic display of metastasises, and sometimes and a primary tumour is kartsinoidnyj a syndrome.